- mtDNA tree Build 17 (18 Feb 2016): subtree L6
Citation: van Oven M, Kayser M. 2009. Updated comprehensive phylogenetic tree of global human mitochondrial DNA variation. Hum Mutat 30(2):E386-E394.
Nucleotide position numbers are consistent with both the rCRS and the RSRS reference sequences.
Mutations are given in forward evolutionary time direction in the format [ancestral base][position number][derived base], e.g. "G15043A".
In case of a transversion, the derived allele is shown in lowercase instead of uppercase, e.g. "C5178a".
Insertions are indicated by the position number preceding the insertion followed by a dot (.), the relative insert position, and the inserted base(s), e.g. "2156.1A".
Deletions are indicated by the letter "d" following the (range of) position number(s) involved, e.g. "A249d" or "8281-8289d".
Mutations that are reversions to an ancestral state (back mutations) are indicated with an exclamation mark (!), two exclamation marks for a double back mutation (!!), etc., e.g. "A15301G!".
Coding-region mutations (np 577-16023) are shown in black; control-region mutations (np 16024-576) in blue.
Mutations between brackets () are recurrent/unstable within the respective clade, or are yet uncertain based on current data.
Mutation motifs in italic are preliminary and are likely to be further refined as additional sequences become available.
The mutations 309.1C(C), 315.1C, AC indels at 515-522, A16182c, A16183c, 16193.1C(C) and C16519T/T16519C were not considered for phylogenetic reconstruction and are therefore excluded from the tree.
Accession numbers provided at the tips of branches are representative examples of mtDNA sequences available at GenBank or from individuals included in HapMap/1000Genomes.
It may be convenient to use the Find function (Ctrl+F) of your browser to search for a particular mutation or haplogroup.
                                                Example accessions
 mt-MRCA (RSRS)                                            
L1'2'3'4'5'6  C146T  C182T  T4312C  T10664C  C10915T  A11914G  G13276A  G16230A                                 
  L2'3'4'5'6  C152T  A2758G  C2885T  G7146A  T8468C                                     
    L2'3'4'6  C195T  A247G  A825t  T8655C  A10688G  C10810T  G13105A  T13506C  G15301A  A16129G  T16187C  C16189T                       
      L3'4'6  G4104A  A7521G                                     
        L3'4  T182C!  T3594C  T7256C  T13650C  T16278C                               
          L3  A769G  A1018G  C16311T                               
            N  G8701A  C9540T  G10398A  C10873T  A15301G!                         
              R  T12705C  T16223C                             
                R0  G73A  A11719G                           
                  HV  T14766C                           
                    H  G2706A  T7028C                       
                      H2  G1438A                       
                        H2a  G4769A                     
                          H2a2  G750A                   
                            H2a2a  G8860A  G15326A               
                              H2a2a1  G263A                rCRS
        L6  T146C!  T152C!  G185c  G709A  C770T  T961C  A1461G  C4964T  T5267C  A6002G  A6284G  C9332T  A10978G  T11116C  C11743T  G12771A  A13710G  C14791T  A14959G  A15244G  T15289C  C15499T  G16048A  T16224C 
          L6a  G207A  T265C                                  EU092773 EU092802
          L6b  C14533a                                    DQ341063 EU092686