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PhyloTree.org -
mtDNA tree Build 17 (18 Feb 2016): subtree N |
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Citation: van Oven M, Kayser M.
2009. Updated comprehensive phylogenetic tree of global human mitochondrial
DNA variation. Hum Mutat
30(2):E386-E394. |
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Nucleotide position numbers are consistent
with both the rCRS and the RSRS reference sequences. |
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Mutations are given in forward evolutionary
time direction in the format [ancestral base][position number][derived base],
e.g. "G15043A". |
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In case of a transversion, the derived allele
is shown in lowercase instead of uppercase, e.g. "C5178a". |
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Insertions are indicated by the position
number preceding the insertion followed by a dot (.), the relative insert
position, and the inserted base(s), e.g. "2156.1A". |
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Deletions are indicated by the letter
"d" following the (range of) position number(s) involved, e.g.
"A249d" or "8281-8289d". |
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Mutations that are reversions to an ancestral
state (back mutations) are indicated with an exclamation mark (!), two
exclamation marks for a double back mutation (!!), etc., e.g.
"A15301G!". |
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Coding-region mutations (np 577-16023) are
shown in black; control-region mutations (np 16024-576) in blue. |
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Mutations between brackets () are
recurrent/unstable within the respective clade, or are yet uncertain based on
current data. |
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Mutation motifs in italic are preliminary and are likely to be further refined as
additional sequences become available. |
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The mutations 309.1C(C), 315.1C, AC indels at
515-522, A16182c, A16183c, 16193.1C(C) and C16519T/T16519C were not
considered for phylogenetic reconstruction and are therefore excluded from
the tree. |
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Accession numbers provided at the tips of
branches are representative examples of mtDNA sequences available at GenBank
or from individuals included in HapMap/1000Genomes. |
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It may be convenient to use the Find function
(Ctrl+F) of your browser to search for a particular mutation or haplogroup. |
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Example accessions |
mt-MRCA (RSRS) |
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L1'2'3'4'5'6 |
C146T
C182T
T4312C T10664C C10915T
A11914G G13276A G16230A |
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L2'3'4'5'6 |
C152T A2758G
C2885T G7146A T8468C |
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L2'3'4'6 |
C195T
A247G
A825t T8655C A10688G
C10810T G13105A T13506C
G15301A A16129G T16187C C16189T |
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L3'4'6 |
G4104A
A7521G |
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L3'4 |
T182C! T3594C
T7256C T13650C T16278C |
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L3 |
A769G
A1018G C16311T |
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N |
G8701A
C9540T G10398A C10873T
A15301G! |
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R |
T12705C
T16223C |
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R0 |
G73A A11719G |
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HV |
T14766C |
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H |
G2706A
T7028C |
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H2 |
G1438A |
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H2a |
G4769A |
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H2a2 |
G750A |
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H2a2a |
G8860A
G15326A |
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H2a2a1 |
G263A |
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rCRS |
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N1'5 |
G1719A |
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N1 |
T10238C
G12501A |
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N5 |
T5063C
A7076G A9545G T11626C
(A13434G) C16111T
T16311C! |
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AY714031 |
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N5a |
T131C
T199C G228A A234G
A374G
A6974G (T13830C) G15119A
T16144C
C16185T C16261T G16319A |
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GU480015 |
GU480020 |
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N2 |
A189G G709A
G5046A C11674T T12414C |
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N3 |
T146C!
A210G C571T T1005C G3357A
G6366A A6806G G7897A
A8653G T8937C G10586A
T14634C T16086C T16172C C16187T!
T16189C! T16217C |
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KC867130 |
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N3a |
T5048C
C9815T A11128G |
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KC867127 |
JQ705752 |
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N3a1 |
G14569A |
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KC867129 |
KC867132 |
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N3b |
T5553C
C9211T T15670C |
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KC867123 |
KC867131 |
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N7 |
A723G
G6570t T11617C A13542G
C14668T C15945T G16129A! (A16318G) |
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N7a |
G75t
T152C! T279C A508G T3396C
G5261A A5390G A6710G
A9254G G9438A A16051G T16063C |
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N7a1 |
G709A
A16166d
A16463G A16466G |
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KC887495 |
KC505118 |
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N7a2 |
T10370C
C16173T
C16355T |
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KC505116 |
KC887473 |
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N7b |
G1503A
G1888A G3391A C5135T
A8483G C12906T C14485T |
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KC505117 |
KC505119 |
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N8 |
A2760G
T3027C T7885C T7961C
A8188G A10398G! A13710G
C15211T T16263C G16274A
T16311C! A16343G |
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JX289118 |
HM030548 |
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N9 |
G5417A |
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N10 |
G750A
A5581G T16172C T16362C |
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N10a |
G185A
A189G
C3543T A3873G A4562G
G7853A G10373A T12136C
A13434G G13928c C14953T
C15211T T16189C! |
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HM030521 |
HM030542 |
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N10b |
C150T
T152C! T199C G709A T2010C
A2707c T4977C A6245G
C8130T T8167C C9459T
T10345C C12092a A14053G
A15226G C16069T
C16278T! C16291a T16298C |
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HM030500 |
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N11 |
C11581a |
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N11a |
T195C! A813G
T6674C A7975G T8618C
A10289G T10908C T14311C
T14431C T14502C T15514C
T15900C C16355T |
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N11a1 |
A12634G
T16189C! |
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HM030536 |
HM030513 |
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N11a2 |
T8928C
A9180G A14220G C16176T C16232T |
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HM030528 |
KF540803 |
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N11b |
C150T
C261T
G3736A T4080C C5234T
T6092C T6620C G7356A
A8512G T8867C A9503G
A9596G T10321C T11204C
C11728T C12401T A14357G
G16129A! C16193T
T16209C C16270T C16291T |
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GU733740 |
GU733776 |
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N13 |
T146C!
T152C! A178G T195C! G2831A
C5704T T6896C T10101C
A11020G A13263G A16066G C16261T
C16290T |
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EF495214 |
JN226143 |
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N14 |
G1598A
G1888A A4917G T5291C
G8251A G8269A A11491G
G14384c C15040T G15884c |
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DQ112753 |
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N21 |
C150T
A337d
A6752G A8701G! A10583G
T13437C G14560A C16193T |
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GQ301885 |
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T195C! |
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GQ301867 |
GQ301887 |
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N21a |
C9512T
G13135A C16291T |
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AP012425 |
GQ301877 |
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N22 |
C150T A942G
A7158G A9254G T11365C
C16168T
T16249C |
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JF739542 |
GQ119034 |
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N22a |
292.1AT C9159T
C12025T A14587G T16017C |
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AP012414 |
AY963578 |
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A |
A235G A663G
A1736G T4248C A4824G
C8794T C16290T G16319A |
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O |
G6755A
C9140T G16213A |
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AY289059 |
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O1 |
T152C!
C509T
G5563A T6221C T15300C
T15852C C15885T G16303A T16362C |
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DQ404447 |
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O1a |
G5460A
A15924G |
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AY289056 |
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S |
T8404C |
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S1 |
G14384c
T16075C |
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AF346963 |
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S1a |
C150g
A189G A215G C271g G8251A
T8506C C15040T T16172C T16311C! |
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JN226144 |
DQ404440 |
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S2 |
C2380T
G3438A T6167C |
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AY289051 |
AF346964 |
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T152C! |
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S3 |
T63C
C64T G66A C151T
T195C!
T710C T5302C T5492C
T8277C 8278.XC T9938C
A10398G! T10786C C11151T
T15204C G15317A T15663C
C15664T T16140C
C16187T! T16189C! C16287T
T16311C! |
AY289066 |
AY289067 |
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S4 |
G1007A
A4181G T5090C C6528T
G7498A C9866T T16172C C16192T
G16319A |
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AY289062 |
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S5 |
A234G
A249d A508G C1375T C3169T
T3593C C3996T G8027A
A10188G A11470G C13770a
C14121T T16243C
C16256T |
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EF495220 |
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X |
T6221C
C6371T A13966G T14470C
T16189C!
C16278T! |
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